1.Xie S#, Zhu Q#, Qu W#, Xu Z, Liu X, Li X, Li S, Ma W, Miao Y, Zhang L, Du X, Dong W, Li H, Zhao C, Wang Y, Fang Y, Zhao S. sRNAPrimerDB: Comprehensive primer design and search web service for small non-coding RNAs.Bioinformatics. 2018,8. doi: 10.1093/bioinformatics/bty852.

2.Ma Y, Zhang S, Zhang K, Fang C, Xie S, Du X, Li X, Ni D, Zhao S. Genomic Analysis To Identify Signatures of Artificial Selection and Loci Associated with Important Economic Traits in Duroc Pigs.G3 (Bethesda). 2018,6;8(11):3617-3625. doi: 10.1534/g3.118.200665.

3.Tang C, Ni M, Xie S, Zhang Y, Zhang C, Ni Z, Chu C, Wu L, Zhou Y, Zhang Y. DICER1 regulates antibacterial function of epididymis by modulating transcription of β-defensins.J Mol Cell Biol. 2018,12. doi: 10.1093/jmcb/mjy048.

4.Ma Y, Gu L, Yang L, Sun C, Xie S, Fang C, Gong Y, Li S. Identifying artificial selection signals in the chicken genome.PLoS One. 2018,26;13(4):e0196215. doi: 10.1371/journal.pone.0196215. eCollection 2018.

5. Zhang C, Zhou Y, Xie S, Yin Q, Tang C, Ni Z, Fei J, Zhang Y. CRISPR/Cas9-mediated genome editing reveals the synergistic effects of β-defensin family members on sperm maturation in rat epididymis.FASEB J. 2018, 32(3):1354-1363. doi: 10.1096/fj.201700936R.

6.Ahmad HI, Ahmad MJ, Asif AR, Adnan M, Iqbal MK, Mehmood K, Muhammad SA, Bhuiyan AA, Elokil A, Du X, Zhao C, Liu X*, Xie S*. A review of CRISPR-based genome editing: survival, evolution and challenges. Curr. Issues Mol. Biol. 2018, 28: 47-68. doi: 10.21775/cimb.028.047.

7. Liu HL, Shen Y, Gao Y, Zhou L, Han XS, Zhao CZ, Yang GJ, Chen YL, Yang H, Xie SS*. Assessing abundance and specificity of different types of sgRNA targeting miRNA precursors. Yi Chuan. 2018 Jul 20;40(7):561-571. doi: 10.16288/j.yczz.17-417. Article in Chinese.


1.Xu J, Yao G, Ru Y, Xie S*. Expression of tamoxifen-inducible CRE recombinase in Lcn5-CreERT2 transgenic mouse caput epididymis. Mol Reprod Dev. 2017, 84(3):257-264. doi:10.1002/mrd.22772.

2. Zhao C, Zheng X, Qu W, Li G, Li X, Miao Y, Han X, Liu X, Li Z, Ma Y, Shao Q, Li H, Sun F*, Xie S*, Zhao S*. CRISPR-offinder: a CRISPR guide RNA design and off-target searching tool for user-defined protospacer adjacent motif. Int J Biol Sci, 2017,13(11):1470-1478. doi:10.7150/ijbs.21312.

3.Chen R, Du J, Ma L, Wang L, Xie S, Yang C, Lan X, Pan C, Dong W. Comparative microRNAome analysis of the testis and ovary of the Chinese giant salamander. Reproduction, 2017,154(3):169-179.doi: 10.1530/REP-17-0109.

4.Cheng Y, Wei Z, Xie S, Peng Y, Yan Y, Qin D, Liu S, Xu Y, Li G, Zhang L. Alleviation of Toxicity Caused by Overactivation of Pparα through Pparα-Inducible miR-181a2. Molecular Therapy-Nucleic Acids, 2017, 9:195-206.DOI:


1.Xie S*, Liu X, Zeng C, Ma Y, Wang H. The application of CRISPR/Cas9 technology in the innovative experimental teaching of molecular biology. Chemisty of life, 2016, 36(1): 117-125. doi: 10.13488/j.smhx.20160119. Article in Chinese.


1.Xie S, Zhang Y, Zhang L, Li G, Zhao C,Ni P, Zhao S.sgRNA design for the CRISPR/Cas9 system and evaluation of its off-target effects. Hereditas (Beijing). 2015, 37(11):1125-36. doi: 10.16288/j.yczz.15-093. Review.

2. Zhao C, Zhang Y, Li G, Chen J, Li J, Ren R, Ni P, Zhao S, Xie S*.Development of a graphical user interface for sgRNAcas9 and its application. Hereditas (Beijing). 2015, 37(10):1061-72. doi: 10.16288/j.yczz.15-292. Article in Chinese.

3. Chu C, Zheng G, Hu S, Zhang J, Xie S, Ma W, Ni M, Tang C, Zhou L, Zhou Y, Liu M, Li Y, Zhang Y. Epididymal Region-Specific miRNA Expression and DNA Methylation and Their Roles in Controlling Gene Expression in Rats. PLoS One. 2015, 10(4):e0124450. doi: 10.1371/journal.pone.0124450.

4.Apopo S, Liu H, Jing L, Du X, Xie S, Gong Y, Xu R, Li S.Identification and profiling of microRNAs associated with white and black plumage pigmentation in the white and black feather bulbs of ducks by RNA sequencing.Anim Genet. 2015 Dec;46(6):627-35. doi: 10.1111/age.12343. Epub 2015 Sep 15.


1. Xie S, Shen B, Zhang C, Huang X, Zhang Y. sgRNAcas9: a software package for designing CRISPR sgRNA and evaluating potential off-target cleavage sites. PLoS One. 2014,9(6):e100448.doi: 10.1371/journal.pone.0100448.


1. Xie S, Xu J, Ma W, Liu Q, Han J, Yao G, Huang X, Zhang Y. Lcn5 promoter directs the region-specific expression of cre recombinase in caput epididymidis of transgenic mice. Biol Reprod. 2013, 88(3):71.doi: 10.1095/biolreprod.112.104034.

2. Zhang J, Xie S, Ma W, Teng Y, Tian Y, Huang X, Zhang Y. A newly identified microRNA,mmu-miR-7578,functions as a negative regulator on inflammatory cytokines tumor necrosis factor-α and interleukin-6 via targeting Egr1 in vivo. J Biol Chem.2013, 288(6):4310-20.doi: 10.1074/jbc.M112.351197.

3. Ma W, Hu S, Yao G, Xie S, Ni M, Liu Q, Gao X, Zhang J, Huang X, Zhang Y. An androgen receptor-microrna-29a regulatory circuitry in mouse epididymis. J Biol Chem. 2013, 288(41):29369-81.doi: 10.1074/jbc.M113.454066.


1. Ma W, Xie S, Ni M, Huang X, Hu S, Liu Q, Liu A, Zhang J, Zhang Y. MicroRNA-29a inhibited epididymal epithelial cell proliferation by targeting nuclear autoantigenic sperm protein (NASP). J Biol Chem. 2012, 287(13):10189-99. doi: 10.1074/jbc.M111.303636.

2.Sun N, Liu D, Chen H, Liu X, Meng F, Zhang X, Chen H, Xie S, Li X, Wu Z. Localization, expression change in PRRSV infection and association analysis of the porcine TAP1 gene. Int J Biol Sci. 2012, 8(1):49-58.doi:10.7150/ijbs.8.49.


1. Xie S, Li X, Liu T, Cao J, Zhong Q, Zhao S. Discovery of porcine microRNAs in multiple tissues by a Solexa deep sequencing approach. PLoS One. 2011, 6(1):e16235. doi: 10.1371/journal.pone.0016235.


1. Xie S, Huang T, Shen Y, Li X, Zhang X, Zhu M, Qin H, Zhao S. Identification and characterization of microRNAs from porcine skeletal muscle.Anim Genet. 2010,41(2):179-90. doi: 10.1111/j.1365-2052.2009.01991.x.


1.Xie S, Li X, Su L, Gu T, Zhao S. A Facile, Rapid and Effective Method for RNA Quality Determination. Journal of Agricultural Biotechnology. 2009, 17 (2):282-287. Article in Chinese.


1.Xie S, Feng Y, Shen Y, Qin H, Zhu M, Zhao S. Cloning of Porcine miRNA let-7b and let-7c by Two Methods. Journal of Agricultural Biotechnology. 2008, 16 (1): 24-31. Article in Chinese.

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