1.Han X, Gao Y, Li G, Xiong Y, Zhao C, Ruan J, Ma Y, Li X, Li C, Zhao S, Xie S*.Enhancing the antibacterial activities of sow milk via site-specifc knock-in of a lactoferrin gene in pigs using CRISPR/Cas9 technology.Cell Biosci, 2020,10:133.

2.Zhao C, Liu H, Xiao T, Wang Z, Nie X, Li X, Qian P, Qin L, Han X, Zhang J, Ruan J, Zhu M, Miao Y, Zuo B, Yang K, Xie S*, Zhao S*. CRISPR screening of porcine sgRNA library identifies host factors associated with Japanese encephalitis virus replication. Nature Communications, 2020, 11:5178. (*Co-Corresponding authors)

3.Xiong Y, Han X, Zhang J, Zhao G, Wang Z, Zhuang R, Nie X, Xie S, Li C, Li X, Liu X, Li K, Zhao S, Ruan J. Identification of ACTB Gene as a Potential Safe Harbor Locus in Pig Genome. Mol Biotechnol, 2020, 26. doi: 10.1007/s12033-020-00276-6.

4.Tao D, Liu J, Nie X, Xu B, Tran-Thi TN, Niu L, Liu X, Ruan J, Lan X, Peng G, Sun L, Ma Y, Li X, Li C, Zhao SH, Xie S*. Application of CRISPR-Cas12a enhanced fluorescence assay coupled with nucleic acid amplification for the sensitive detection of African swine fever virus. ACS Synth Biol, 2020, 9(9):2339-2350.

5.Zhang S, Zhang K, Peng X, Zhan Hui, Lu Jia, Xie S, Zhao S, Li X, Ma Y. Selective sweep analysis reveals extensive parallel selection traits between Large white and Duroc. Evolutionary Applications, 2020, doi: 10.1111/eva.13085.

6.Zhan H, Zhang S, Zhang K, Peng X, Xie S, Li X, Zhao S, Ma Y. Genome-Wide Patterns of Homozygosity and Relevant Characterizations on the Population Structure in Piétrain Pigs. Genes (Basel), 2020, 11(5):577.

7.Chu C, Yu L, Henry-Berger J, Ru Y, Kocer A, Champroux A, Li Z, He M, Xie S, Ma W, Ni M, Ni Z, Guo Y, Fei Z, Gou L, Liu Q, Sharma S, Zhou Y, Liu M, Chen C, Eamens A, Nixon B, Zhou Y, Drevet J, Zhang Y. Knockout of glutathione peroxidase 5 down-regulates the piRNAs in the caput epididymidis of aged mice. Asian J Androl, 2020, doi: 10.4103/aja.aja_3_20.

8.Zhang D, Hussain A, Manghwar H, Xie K, Xie S, Zhao S, Larkin RM, Qing P, Jin S, Ding F. Genome editing with the CRISPR-Cas system: an art, ethics and global regulatory perspective. Plant Biotechnol J, 2020, 18(8):1651-1669.

9.Fu L, Wang H, Liao Y, Zhou P, Xu Y, Zhao Y, Xie S, Zhao S, Li X. miR-208b modulating skeletal muscle development and energy homoeostasis through targeting distinct targets. RNA Biol, 2020, 17(5):743-754.


10. Zhao C, Wang Y, Nie X, Han X, Liu H, Li G, Yang G, Ruan J, Ma Y, Li X, Cheng H, Zhao S, Fang Y*, Xie S*. Evaluation of the effects of sequence length and microsatellite instability on single-guide RNA activity and specificity. Int J Biol Sci, 2019, 15(12):2641-2653. (*Co-Corresponding authors)

11. Zheng B, Wang X, Liu Y, Li Y, Long S, Gu C, Ye J, Xie S, Cao S. Japanese Encephalitis Virus infection induces inflammation of swine testis through RIG-I—NF-ĸB signaling pathway.Veterinary Microbiology, 2019, 238:108430.

12. Han X, Xiong Y, Zhao C, Xie S, Li C, Li X, Liu X, Li K, Zhao S, Ruan J. Identification of Glyceraldehyde-3-Phosphate Dehydrogenase Gene as an Alternative Safe Harbor Locus in Pig Genome. Genes (Basel), 2019,10(9):660.

13. Gao H, Wen H, Cao C, Dong D, Yang C, Xie S, Zhang J, Huang X, Huang X, Yuan S, Dong W. Overexpression of MicroRNA-10a in Germ Cells Causes Male Infertility by Targeting Rad51 in Mouse and Human. Front Physiol, 2019, 10:765.

14. Zhao C, Xie S, Wu H, Luan Y, Hu S, Ni J, Lin R, Zhao S, Zhang D, Li X. Quantification of allelic differential expression using a simple fluorescence primer PCR-RFLP-based method. Sci. Rep, 2019, 9(1):6334.

15. Ma H, Zhang S, Zhang K, Zhan H, Peng X, Xie S, Li X, Zhao S, Ma Y. Identifying selection signatures for backfat thickness in Yorkshire pigs highlights new regions affecting fat metabolism. Genes (Basel), 2019, 10(4):254.

16. Xie S#, Zhu Q#, Qu W#, Xu Z, Liu X, Li X, Li S, Ma W, Miao Y, Zhang L, Du X, Dong W, Li H, Zhao C, Wang Y, Fang Y, Zhao S. sRNAPrimerDB: Comprehensive primer design and search web service for small non-coding RNAs. Bioinformatics, 2019, 35(9):1566-1572. (#Co-first authors)


17. Ma Y, Zhang S, Zhang K, Fang C, Xie S, Du X, Li X, Ni D, Zhao S. Genomic analysis to identify signatures of artificial selection and loci associated with important economic traits in Duroc pigs. G3 (Bethesda), 2018, 8(11):3617-3625.

18. Tang C, Ni M, Xie S, Zhang Y, Zhang C, Ni Z, Chu C, Wu L, Zhou Y, Zhang Y. DICER1 regulates antibacterial function of epididymis by modulating transcription of β-defensins. J. Mol. Cell Biol, 2018, 11(5):408-420.

19. Ma Y, Gu L, Yang L, Sun C, Xie S, Fang C, Gong Y, Li S. Identifying artificial selection signals in the chicken genome. PLoS One, 2018,13(4):e0196215.

20. Ahmad HI, Ahmad MJ, Asif AR, Adnan M, Iqbal MK, Mehmood K, Muhammad SA, Bhuiyan AA, Elokil A, Du X, Zhao C, Liu X*, Xie S*. A review of CRISPR-based genome editing: Survival, evolution and challenges. Curr. Issues Mol. Biol, 2018, 28:47-68. (*Co-Corresponding authors)

21. Zhang C, Zhou Y, Xie S, Yin Q, Tang C, Ni Z, Fei J, Zhang Y. CRISPR/Cas9-mediated genome editing reveals the synergistic effects of β-defensin family members on sperm maturation in rat epididymis. FASEB J, 2018, 32(3):1354-1363.


22. Cheng Y, Wei Z, Xie S, Peng Y, Yan Y, Qin D, Liu S, Xu Y, Li G, Zhang L. Alleviation of toxicity caused by overactivation of Pparα through Pparα-inducible miR-181a2. Molecular Therapy-Nucleic Acids, 2017, 9:195-206.

23. Zhao C, Zheng X, Qu W, Li G, Li X, Miao Y, Han X, Liu X, Li Z, Ma Y, Shao Q, Li H, Sun F*, Xie S*, Zhao S*. CRISPR-offinder: A CRISPR guide RNA design and off-target searching tool for user-defined protospacer adjacent motif. Int. J. Biol. Sci, 2017, 13(11):1470-1478. (*Co-Corresponding authors)

24. Xu J, Yao G, Ru Y, Xie S*. Expression of tamoxifen-inducible CRE recombinase in Lcn5-CreERT2 transgenic mouse caput epididymis. Mol. Reprod. Dev, 2017, 84(3):257-264.

25. Chen R, Du J, Ma L, Wang L, Xie S, Yang C, Lan X, Pan C, Dong W. Comparative microRNAome analysis of the testis and ovary of the Chinese giant salamander. Reproduction, 2017, 154(3):169-179.


26. Chu C, Zheng G, Hu S, Zhang J, Xie S, Ma W, Ni M, Tang C, Zhou L, Zhou Y, Liu M, Li Y, Zhang Y. Epididymal region-specific miRNA expression and DNA methylation and their roles in controlling gene expression in rats. PLoS One, 2015, 10(4):e0124450.

27.Apopo S, Liu H, Jing L, Du X, Xie S, Gong Y, Xu R, Li S. Identification and profiling of microRNAs associated with white and black plumage pigmentation in the white and black feather bulbs of ducks by RNA sequencing. Anim Genet, 2015,46(6):627-35.


28. Xie S, Shen B, Zhang C, Huang X, Zhang Y. sgRNAcas9: A software package for designing CRISPR sgRNA and evaluating potential off-target cleavage sites. PLoS One, 2014, 9(6):e100448.


29. Ma W, Hu S, Yao G, Xie S, Ni M, Liu Q, Gao X, Zhang J, Huang X, Zhang Y. An androgen receptor-microrna-29a regulatory circuitry in mouse epididymis. J. Biol. Chem, 2013, 288(41):29369-29381.

30. Xie S#, Xu J#, Ma W, Liu Q, Han J, Yao G, Huang X, Zhang Y. Lcn5 promoter directs the region-specific expression of cre recombinase in caput epididymidis of transgenic mice. Biol. Reprod, 2013, 88(3):71. (#co-first author)

31. Zhang J, Xie S, Ma W, Teng Y, Tian Y, Huang X, Zhang Y. A newly identified microRNA,mmu-miR-7578,functions as a negative regulator on inflammatory cytokines tumor necrosis factor-α and interleukin-6 via targeting Egr1 in vivo. J. Biol. Chem, 2013, 288(6):4310-20.


32. Sun N, Liu D, Chen H, Liu X, Meng F, Zhang X, Chen H, Xie S, Li X, Wu Z. Localization, expression change in PRRSV infection and association analysis of the porcine TAP1 gene. Int. J. Biol. Sci, 2012, 8(1):49-58.

33. Ma W, Xie S, Ni M, Huang X, Hu S, Liu Q, Liu A, Zhang J, Zhang Y. MicroRNA-29a inhibited epididymal epithelial cell proliferation by targeting nuclear autoantigenic sperm protein (NASP). J. Biol. Chem, 2012, 287(13):10189-99.


34. Xie S#, Li X#, Liu T, Cao J, Zhong Q, Zhao S. Discovery of porcine microRNAs in multiple tissues by a Solexa deep sequencing approach. PLoS One, 2011, 6(1):e16235. (#co-first author)


35. Xie S, Huang T, Shen Y, Li X, Zhang X, Zhu M, Qin H, Zhao S. Identification and characterization of microRNAs from porcine skeletal muscle. Anim. Genet, 2010, 41(2):179-90.‍


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